Cystic and alveolar echinococcosis: Successes and continuing challenges

Cystic and alveolar echinococcosis: Successes and continuing challenges

1 Department of Veterinary Integrative Biosciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America, 2 WHO Collaborating Centre for the epidemiology, detection and control of cystic and alveolar echinococcosis (in humans and animals); European Reference Laboratory for Parasites; Istituto Superiore di Sanita’, Rome, Ita...

The Present Situation of Alveolar and Cystic Echinococcosis in Europe

(pets, farm cats, etc) and, therefore, the infection risk is usually unknown. Other wildlife species are numerically of no importance as final hosts in Europe: the raccoon dog (Nyctereutes procyonoides), an accidentally introduced caniid from East Asia was recently confirmed as a natural host of E. multilocularis in Germany. The wolf (Canis lupus), lynx (Lynx spp) and wild cat (Felis sylvestris...

Guidelines for treatment of cystic and alveolar echinococcosis in humans. WHO Informal Working Group on Echinococcosis.

Summarized in this article are recent experiences in the treatment of human cystic echinococcosis (CE) and alveolar echinococcosis (AE) of the liver caused by the metacestode stages of Echinococcus granulosus and E. multilocularis, respectively. For CE, surgery remains the first choice for treatment with the potential to remove totally the parasite and completely cure the patient. However, chem...

Alveolar echinococcosis ,

Docking: successes and challenges.

The state of the art of various computational aspects of docking-based virtual screening of database of small molecules is presented. The review encompasses the different search algorithms and the scoring functions used in docking methods and their applications to protein and nucleic acid drug targets. Recent progress made in the development and application of methods to include target flexibil...